Embryo health Test have been recently prevalent in Iran. The test Inspect prevalent chromosome disorders during pregnancy (early days of the 10th week and end of the 23rd week). Although the test is not an expert method but as an screening test it helps much in distinguishing embryos with chromosome disorder.
Embryo health assessment protocol from the genetic disorder point of view
Embryo genetic disorder inspection fall into 2 sections:
Invasive - In this method, specific amount of Amniotic fluid from the embryo sack, is extracted with syringe by expert physician and sent to the Lab. to inspect the DNA. Since there is 1% risk of abortion, the method is called Invasive
Though, the invasive method is an effective way to a determinate chromosome disorder diagnosis, but 1% of risk for mothers whom impregnated by IVF and also mothers whose chances for pregnancy is low, seems irrational. In addition this method is costly and risky as an screening test. Therefor Non-Invasive method is recommended.
Non-Invasive - This method is based on two factors: sonography findings & mother's blood tests.
This method is not a determinate chromosome disorder diagnosis. It is a statistic analysis test which monitors the probabilities of disorders. Cases with positive result can be candidate for invasive method.
sonography test inspects embryo in different situations. one of them is called NT (early 3 months of pregnancy) which checks the width of neck wrinkles. Embryo health test by mother's blood sample is based on hormones measurement and consists following items:
- Double Test
- Combined Test
- Triple Test
- Quad Marker
- Integrated Test
- Non Invasive Prenatal Test (NIPT) or Cell free DNA